Peter Schmieder: Research

Research Focus
The group Solution NMR spectroscopy uses the full repertoire of solution state NMR techniques in conjunction with a variety of labelling patterns to address questions of biological and pharmacological importance. These range from the development of new techniques for solution state NMR for to the elucidation of the constitution and configuration of biological active peptides to and the determination of the three-dimensional structure of peptides and proteins.

List of funding

Currently funded Projects

NMR spectroscopic investigation of micropolymorphism-dependent dynamics of human major histocompatibility antigens
Structure determination and domain interaction of the photochromic protein YtvA from Bacilus subtilis

Still running

Structure of the chromophore in the phytochrome Cph1 from Synechocystis sp. PCC6803
Control of protein-protein-interactions through conformational changes induced by light: photo-switchable ligand molecules for PDZ domains
Regulation of phytochrome biological function through light-induced conformational changes: A study using solid-state NMR spectroscopy

Other Projects

Molecular and structural pattern of claudin-claudin interactions in tight junctions
Amino acid selective pulse sequences for an automated assignment of protein spectra
Antimicrobial peptides: Structure of antimicrobial peptides bound to detergent micells
Structure of cyanobacterial peptides
31P-NMR of lake sediments

Cooperation partners

within the FMP outside the FMP
Margitta Dathe Karola Rück-Braun (TU Berlin)
Michael Beyermann Michael Hupfer (IGB Berlin)
Gerd Krause Jon Hughes (U Giessen)
Ronald Kühne Tilman Lamparter (FU Berlin)
Wolfgang Gärtner (MPI Mülheim)
Peter Hildebrandt (TU Berlin)
Hans von Döhren (TU Berlin)
  Barbara Uchanska-Ziegler/Andreas Ziegler (FU Berlin)

last changes 26.04.2008, Peter Schmieder